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Oligodeoxyribonucleotide probe accessibility on a three-dimensional DNA microarray surface and the effect of hybridization time on the accuracy of expression ratios

BACKGROUND: DNA microarrays are now routinely used to monitor the transcript levels of thousands of genes simultaneously. However, the array fabrication method, hybridization conditions, and oligodeoxyribonucleotide probe length can impact the performance of a DNA microarray platform. RESULTS: We de...

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Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Dorris, David R, Nguyen, Allen, Gieser, Linn, Lockner, Randall, Lublinsky, Anna, Patterson, Marcus, Touma, Edward, Sendera, Timothy J, Elghanian, Robert, Mazumder, Abhijit
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165584/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12801425/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6750-3-6
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