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Oligodeoxyribonucleotide probe accessibility on a three-dimensional DNA microarray surface and the effect of hybridization time on the accuracy of expression ratios

BACKGROUND: DNA microarrays are now routinely used to monitor the transcript levels of thousands of genes simultaneously. However, the array fabrication method, hybridization conditions, and oligodeoxyribonucleotide probe length can impact the performance of a DNA microarray platform. RESULTS: We de...

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Détails bibliographiques
Auteurs principaux: Dorris, David R, Nguyen, Allen, Gieser, Linn, Lockner, Randall, Lublinsky, Anna, Patterson, Marcus, Touma, Edward, Sendera, Timothy J, Elghanian, Robert, Mazumder, Abhijit
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC165584/
https://ncbi.nlm.nih.gov/pubmed/12801425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-3-6
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