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Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2)

BACKGROUND: Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed at higher level in most of the tumors analyzed to date compared to normal tissues. Existence of a relationship between PTTG levels and tumor angiogenesis and metastasis has been reported. However, the mechanis...

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Detalhes bibliográficos
Main Authors: Malik, Mohammad T, Kakar, Sham S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1654177/
https://ncbi.nlm.nih.gov/pubmed/17096843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-61
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