Microtubule Network Facilitates Nuclear Targeting of Human Cytomegalovirus Capsid

We assessed the requirement of the host cytoskeleton for the intracytosolic transport of incoming human cytomegalovirus (HCMV) capsids. Treatments with microtubule (MT)-depolymerizing drugs nocodazole and colchicine led to a drastic decrease in levels of IE1 antigen, whereas cytochalasin B had no ef...

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Detalhes bibliográficos
Main Authors: Ogawa-Goto, K., Tanaka, K., Gibson, W., Moriishi, E., Miura, Y., Kurata, T., Irie, S., Sata, T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165267/
https://ncbi.nlm.nih.gov/pubmed/12857923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8541-8547.2003
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