Improved Protection of Rhesus Macaques against Intrarectal Simian Immunodeficiency Virus SIV(mac251) Challenge by a Replication-Competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag Recombinant Priming/gp120 Boosting Regimen

In this study we investigated the ability of a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen to induce protective immunity in rhesus macaques against pathogenic simian immunodeficiency virus(mac251). Immunization of macaques by two sequential admi...

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Autors principals: Zhao, Jun, Pinczewski, Joel, Gómez-Román, Victor R., Venzon, David, Kalyanaraman, V. S., Markham, Phillip D., Aldrich, Kristine, Moake, Matthew, Montefiori, David C., Lou, Yuanmei, Pavlakis, George N., Robert-Guroff, Marjorie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC165263/
https://ncbi.nlm.nih.gov/pubmed/12857905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8354-8365.2003
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