Hantavirus-Specific CD8(+)-T-Cell Responses in Newborn Mice Persistently Infected with Hantaan Virus

The relationship between virus-specific CD8(+)-T-cell responses and viral persistence was studied in mice by using Hantaan virus (HTNV). We first established a simple method for measuring levels of virus-specific CD8(+) T cells by flow cytometry. Next, to produce a mouse model of persistent HTNV inf...

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Bibliographic Details
Main Authors: Araki, Koichi, Yoshimatsu, Kumiko, Lee, Byoung-Hee, Kariwa, Hiroaki, Takashima, Ikuo, Arikawa, Jiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165253/
https://ncbi.nlm.nih.gov/pubmed/12857910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8408-8417.2003
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