The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts

Activation of class II gene transcription may involve alleviation of transcription repression as well as stimulation of the assembly and function of the general RNA polymerase (RNAP) II transcription machinery. Here, we investigated whether activator-reversible transcription repression by NC2 (Dr1/D...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Castaño, Enrique, Gross, Petra, Wang, Zhengxin, Roeder, Robert G., Oelgeschläger, Thomas
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16520/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10852970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.140202297
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