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Depletion of a Polo-like Kinase in Candida albicans Activates Cyclase-dependent Hyphal-like Growth

Morphogenesis in the fungal pathogen Candida albicans is an important virulence-determining factor, as a dimorphic switch between yeast and hyphal growth forms can increase pathogenesis. We identified CaCDC5, a cell cycle regulatory polo-like kinase (PLK) in C. albicans and demonstrate that shutting...

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Auteurs principaux: Bachewich, Catherine, Thomas, David Y., Whiteway, Malcolm
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC165105/
https://ncbi.nlm.nih.gov/pubmed/12802083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-05-0076
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