p38 Mitogen-Activated Protein Kinase Mediates Cell Death and p21-Activated Kinase Mediates Cell Survival during Chemotherapeutic Drug-induced Mitotic Arrest

Activation of the mitotic checkpoint by chemotherapeutic drugs such as taxol causes mammalian cells to arrest in mitosis and then undergo apoptosis. However, the biochemical basis of chemotherapeutic drug-induced cell death is unclear. Herein, we provide new evidence that both cell survival and cell...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Principais autores:	Deacon, Karl, Mistry, Pratibha, Chernoff, Jonathan, Blank, Jonathan L., Patel, Rajnikant
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Cell Biology 2003
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12802076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-10-0653
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