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A Novel Dynein Light Intermediate Chain Colocalizes with the Retrograde Motor for Intraflagellar Transport at Sites of Axoneme Assembly in Chlamydomonas and Mammalian Cells

The assembly of cilia and flagella depends on bidirectional intraflagellar transport (IFT). Anterograde IFT is driven by kinesin II, whereas retrograde IFT requires cytoplasmic dynein 1b (cDHC1b). Little is known about how cDHC1b interacts with its cargoes or how it is regulated. Recent work identif...

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Hlavní autoři: Perrone, Catherine A., Tritschler, Douglas, Taulman, Patrick, Bower, Raqual, Yoder, Bradley K., Porter, Mary E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC165096/
https://ncbi.nlm.nih.gov/pubmed/12802074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0682
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