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Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals

Transcript elongation by RNA polymerase is discontinuous and interrupted by pauses that play key regulatory roles. We show here that two different classes of pause signals punctuate elongation. Class I pauses, discovered in enteric bacteria, depend on interaction of a nascent RNA structure with RNA...

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Detalhes bibliográficos
Main Authors: Artsimovitch, Irina, Landick, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16504/
https://ncbi.nlm.nih.gov/pubmed/10860976
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