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Aggrecanases and cartilage matrix degradation

The loss of extracellular matrix macromolecules from the cartilage results in serious impairment of joint function. Metalloproteinases called 'aggrecanases' that cleave the Glu(373)–Ala(374 )bond of the aggrecan core protein play a key role in the early stages of cartilage destruction in r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nagase, Hideaki, Kashiwagi, Masahide
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC165039/
https://ncbi.nlm.nih.gov/pubmed/12718749
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