The 1.3-Angstrom-Resolution Crystal Structure of β-Ketoacyl-Acyl Carrier Protein Synthase II from Streptococcus pneumoniae

The β-ketoacyl-acyl carrier protein synthases are members of the thiolase superfamily and are key regulators of bacterial fatty acid synthesis. As essential components of the bacterial lipid metabolic pathway, they are an attractive target for antibacterial drug discovery. We have determined the 1.3...

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Autors principals: Price, Allen C., Rock, Charles O., White, Stephen W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164876/
https://ncbi.nlm.nih.gov/pubmed/12837788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4136-4143.2003
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