Mechanisms of Activation of Phosphoenolpyruvate Carboxykinase from Escherichia coli by Ca(2+) and of Desensitization by Trypsin

The 1.8-Å resolution structure of the ATP-Mg(2+)-Ca(2+)-pyruvate quinary complex of Escherichia coli phosphoenolpyruvate carboxykinase (PCK) is isomorphous to the published complex ATP-Mg(2+)-Mn(2+)-pyruvate-PCK, except for the Ca(2+) and Mn(2+) binding sites. Ca(2+) was formerly implicated as a pos...

Full description

Saved in:
Bibliographic Details
Main Authors: Sudom, Athena, Walters, Robert, Pastushok, Landon, Goldie, Douglas, Prasad, Lata, Delbaere, Louis T. J., Goldie, Hughes
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC164867/
https://ncbi.nlm.nih.gov/pubmed/12837799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4233-4242.2003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items