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Nova Regulates GABA(A) Receptor γ2 Alternative Splicing via a Distal Downstream UCAU-Rich Intronic Splicing Enhancer

Nova is a neuron-specific RNA binding protein targeted in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia, which is characterized by failure of inhibition of brainstem and spinal motor systems. Here, we have biochemically confirmed the observation that splicing regul...

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Udgivet i:Mol Cell Biol
Principais autores: Dredge, B. Kate, Darnell, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.13.4687-4700.2003
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