Schizosaccharomyces pombe Checkpoint Response to DNA Interstrand Cross-Links

Drugs that produce covalent interstrand cross-links (ICLs) in DNA remain central to the treatment of cancer, but the cell cycle checkpoints activated by ICLs have received little attention. We have used the fission yeast, Schizosaccharomyces pombe, to elucidate the checkpoint responses to the ICL-in...

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Bibliographische Detailangaben
Hauptverfasser: Lambert, Sarah, Mason, Sarah J., Barber, Louise J., Hartley, John A., Pearce, Jackie A., Carr, Anthony M., McHugh, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
DNA Dynamics and Chromosome Structure
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164842/
https://ncbi.nlm.nih.gov/pubmed/12808110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4728-4737.2003
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