Nuclear Export of Vpr Is Required for Efficient Replication of Human Immunodeficiency Virus Type 1 in Tissue Macrophages

Retroviruses must gain access to the host cell nucleus for subsequent replication and viral propagation. Human immunodeficiency virus type 1 (HIV-1) and other primate lentiviruses are distinguished from the gammaretroviruses by their ability to infect nondividing cells such as macrophages, an import...

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Main Authors: Sherman, Michael P., de Noronha, Carlos M. C., Eckstein, Lauren A., Hataye, Jason, Mundt, Pamela, Williams, Samuel A. F., Neidleman, Jason A., Goldsmith, Mark A., Greene, Warner C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC164827/
https://ncbi.nlm.nih.gov/pubmed/12805458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7582-7589.2003
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