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The Influenza A Virus PB1-F2 Protein Targets the Inner Mitochondrial Membrane via a Predicted Basic Amphipathic Helix That Disrupts Mitochondrial Function

The 11th influenza A virus gene product is an 87-amino-acid protein provisionally named PB1-F2 (because it is encoded by an open reading frame overlapping the PB1 open reading frame). A significant fraction of PB1-F2 localizes to the inner mitochondrial membrane in influenza A virus-infected cells....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Gibbs, James S., Malide, Daniela, Hornung, Felicita, Bennink, Jack R., Yewdell, Jonathan W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805420/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7214-7224.2003
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