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High-Frequency Genetic Recombination and Reactivation of Orthopoxviruses from DNA Fragments Transfected into Leporipoxvirus-Infected Cells

Poxvirus DNA is not infectious because establishing an infection requires the activities of enzymes packaged in the virion. This barrier can be overcome by transfecting virus DNA into cells previously infected with another poxvirus, since the resident virus can provide the trans-acting systems neede...

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Main Authors: Yao, Xiao-Dan, Evans, David H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC164822/
https://ncbi.nlm.nih.gov/pubmed/12805426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7281-7290.2003
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