Lentivirus Vectors Incorporating the Immunoglobulin Heavy Chain Enhancer and Matrix Attachment Regions Provide Position-Independent Expression in B Lymphocytes

In the present studies we developed lentivirus vectors with regulated, consistent transgene expression in B lymphocytes by incorporating the immunoglobulin heavy chain enhancer (Eμ) with and without associated matrix attachment regions (EμMAR) into lentivirus vectors. Incorporation of these fragment...

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Autors principals: Lutzko, Carolyn, Senadheera, Dinithi, Skelton, Dianne, Petersen, Denise, Kohn, Donald B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Gene Therapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164820/
https://ncbi.nlm.nih.gov/pubmed/12805432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7341-7351.2003
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