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Activation of Tumor Antigen-Specific Cytotoxic T Lymphocytes (CTLs) by Human Dendritic Cells Infected with an Attenuated Influenza A Virus Expressing a CTL Epitope Derived from the HER-2/neu Proto-Oncogene

The development of cancer vaccines requires approaches to induce expansion and functional differentiation of tumor antigen-specific cytotoxic T lymphocyte (CTL) effectors which posses cytolytic capability and produce cytokines. Efficient induction of such cells is hindered by the poor immunogenicity...

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Udgivet i:J Virol
Principais autores: Efferson, Clay L., Schickli, Jeanne, Ko, Byung Kyum, Kawano, Kouichiro, Mouzi, Sara, Palese, Peter, García-Sastre, Adolfo, Ioannides, Constantin G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805440/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7411-7424.2003
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