Identification of a Single Amino Acid Change in the Human Respiratory Syncytial Virus L Protein That Affects Transcriptional Termination

Infectious Human respiratory syncytial virus (HRSV) with an aberrant RNA synthesis pattern was recovered from a cDNA clone. The virus displayed increased levels of polycistronic readthrough mRNAs resulting from failure of the polymerase to terminate transcription efficiently at the gene ends. An asp...

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Main Authors: Cartee, Tara L., Megaw, A. George, Oomens, A. G. P., Wertz, Gail W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC164798/
https://ncbi.nlm.nih.gov/pubmed/12805433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7352-7360.2003
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