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Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences

The antigenic diversity of human immunodeficiency virus type 1 (HIV-1) represents a significant challenge for vaccine design as well as the comprehensive assessment of HIV-1-specific immune responses in infected persons. In this study we assessed the impact of antigen variability on the characteriza...

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Autors principals: Altfeld, Marcus, Addo, Marylyn M., Shankarappa, Raj, Lee, Paul K., Allen, Todd M., Yu, Xu G., Rathod, Almas, Harlow, Jason, O'Sullivan, Kristin, Johnston, Mary N., Goulder, Philip J. R., Mullins, James I., Rosenberg, Eric S., Brander, Christian, Korber, Bette, Walker, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164796/
https://ncbi.nlm.nih.gov/pubmed/12805431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7330-7340.2003
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