Tax Recruitment of CBP/p300, via the KIX Domain, Reveals a Potent Requirement for Acetyltransferase Activity That Is Chromatin Dependent and Histone Tail Independent

Robust transcription of human T-cell leukemia virus type 1 (HTLV-1) genome requires the viral transactivator Tax. Although Tax has been previously shown to interact with the KIX domain of CBP/p300 in vitro, the precise functional relevance of this interaction remains unclear. Using two distinct appr...

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Detalhes bibliográficos
Main Authors: Georges, Sara A., Giebler, Holli A., Cole, Philip A., Luger, Karolin, Laybourn, Paul J., Nyborg, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164760/
https://ncbi.nlm.nih.gov/pubmed/12724399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3392-3404.2003
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