Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene

Most sporadic colon adenomas acquire mutations in the adenomatous polyposis coli gene (APC) and show defects in APC-dependent signaling. APC influences the expression of several genes, including the c-myc oncogene and its antagonist Mad1. Ornithine decarboxylase (ODC), the first enzyme in polyamine...

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Bibliografiske detaljer
Main Authors: Martínez, María Elena, O'Brien, Thomas G., Fultz, Kimberly E., Babbar, Naveen, Yerushalmi, Hagit, Qu, Ning, Guo, Yongjun, Boorman, David, Einspahr, Janine, Alberts, David S., Gerner, Eugene W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164678/
https://ncbi.nlm.nih.gov/pubmed/12810952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332465100
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