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From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression

According to the present view, metastasis marks the end in a sequence of genomic changes underlying the progression of an epithelial cell to a lethal cancer. Here, we aimed to find out at what stage of tumor development transformed cells leave the primary tumor and whether a defined genotype corresp...

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Detalhes bibliográficos
Main Authors: Schmidt-Kittler, Oleg, Ragg, Thomas, Daskalakis, Angela, Granzow, Martin, Ahr, Andre, Blankenstein, Thomas J. F., Kaufmann, Manfred, Diebold, Joachim, Arnholdt, Hans, Müller, Peter, Bischoff, Joachim, Harich, Detlev, Schlimok, Günter, Riethmüller, Gert, Eils, Roland, Klein, Christoph A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164657/
https://ncbi.nlm.nih.gov/pubmed/12808139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1331931100
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