Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence

Despite their high degree of genomic similarity, reminiscent of their relatively recent separation from each other (≈6 million years ago), the molecular basis of traits unique to humans vs. their closest relative, the chimpanzee, is largely unknown. This report describes a large-scale single-contig...

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Detalhes bibliográficos
Main Authors: Anzai, Tatsuya, Shiina, Takashi, Kimura, Natsuki, Yanagiya, Kazuyo, Kohara, Sakae, Shigenari, Atsuko, Yamagata, Tetsushi, Kulski, Jerzy K., Naruse, Taeko K., Fujimori, Yoshifumi, Fukuzumi, Yasuhito, Yamazaki, Masaaki, Tashiro, Hiroyuki, Iwamoto, Chie, Umehara, Yumi, Imanishi, Tadashi, Meyer, Alice, Ikeo, Kazuho, Gojobori, Takashi, Bahram, Seiamak, Inoko, Hidetoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164652/
https://ncbi.nlm.nih.gov/pubmed/12799463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1230533100
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