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Developing an energy landscape for the novel function of a (β/α)(8) barrel: Ammonia conduction through HisF

HisH–hisF is a multidomain globular protein complex; hisH is a class I glutamine amidotransferase that hydrolyzes glutamine to form ammonia, and hisF is a (β/α)(8) barrel cyclase that completes the ring formation of imidizole glycerol phosphate synthase. Together, hisH and hisF form a glutamine amid...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Amaro, Rommie, Tajkhorshid, Emad, Luthey-Schulten, Zaida
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12799468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1331150100
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