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Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues

Mammals contain two methionine sulfoxide (MetO) reductases, MsrA and MsrB, that catalyze the thioredoxin-dependent reduction of the S-MetO and R-MetO derivatives, respectively, to methionine. The major mammalian MsrB is a selenoprotein (except in the heart). Here, we show that there is a loss of Msr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moskovitz, Jackob, Stadtman, Earl R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164613/
https://ncbi.nlm.nih.gov/pubmed/12792026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332607100
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