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RNA recognition by designed peptide fusion creates "artificial" tRNA synthetase

The genetic code was established through aminoacylations of RNA substrates that emerged as tRNAs. The 20 aminoacyl-tRNA synthetases (one for each amino acid) are ancient proteins, the active-site domain of which catalyzes formation of an aminoacyl adenylate that subsequently reacts with the 3′ end o...

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מידע ביבליוגרפי
Main Authors: Frugier, Magali, Giegé, Richard, Schimmel, Paul
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC164610/
https://ncbi.nlm.nih.gov/pubmed/12796515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332771100
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