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d-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors

d-serine has been proposed as an endogenous modulator of N-methyl-d-aspartate (NMDA) receptors in many brain regions, but its presence and function in the vertebrate retina have not been characterized. We have detected d-serine and its synthesizing enzyme, serine racemase, in the retinas of several...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Stevens, Eric R., Esguerra, Manuel, Kim, Paul M., Newman, Eric A., Snyder, Solomon H., Zahs, Kathleen R., Miller, Robert F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12750462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1237052100
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