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β3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice

Hyperlipidemia promotes the chronic inflammatory disease atherosclerosis through poorly understood mechanisms. Atherogenic lipoproteins activate platelets, but it is unknown whether platelets contribute to early inflammatory atherosclerotic lesions. To address the role of platelet aggregation in die...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Weng, Sherry, Zemany, Laura, Standley, Kara N., Novack, Deborah V., La Regina, Marie, Bernal-Mizrachi, Carlos, Coleman, Trey, Semenkovich, Clay F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164515/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12746502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1137612100
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