Susceptibility to tuberculosis: A locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs

The mouse DBA/2 (D2) strain is very susceptible to infection with virulent Mycobacterium tuberculosis, whereas C57BL/6 (B6) is much more resistant. Infection of D2 and B6 mice with M. tuberculosis H37Rv by the respiratory route is biphasic: during the first 3 weeks, there is rapid bacterial growth i...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Mitsos, Loukia-Maria, Cardon, Lon R., Ryan, Lynn, LaCourse, Ronald, North, Robert J., Gros, Philippe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12740444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1031727100
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