Structural basis of albumin–thyroxine interactions and familial dysalbuminemic hyperthyroxinemia

Human serum albumin (HSA) is the major protein component of blood plasma and serves as a transporter for thyroxine and other hydrophobic compounds such as fatty acids and bilirubin. We report here a structural characterization of HSA–thyroxine interactions. Using crystallographic analyses we have id...

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Bibliographische Detailangaben
Hauptverfasser: Petitpas, Isabelle, Petersen, Charles E., Ha, Chung-Eun, Bhattacharya, Ananyo A., Zunszain, Patricia A., Ghuman, Jamie, Bhagavan, Nadhipuram V., Curry, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164465/
https://ncbi.nlm.nih.gov/pubmed/12743361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1137188100
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