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Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering

YOR068c, termed VAM10 (altered vacuole morphology), lies within the VPS5 gene on the opposite DNA strand. VAM10 deletion causes vacuole fragmentation in vivo. The in vitro fusion of purified yeast vacuoles is stimulated by recombinant Vam10p and blocked by antibody to Vam10p. Vam10p acts early in th...

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Bibliographic Details
Main Authors: Kato, Masashi, Wickner, William
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC164458/
https://ncbi.nlm.nih.gov/pubmed/12748377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1132162100
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