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ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays

Extension of lamellipodia, an important dissipative process in cell motility, is driven by the turnover of a polarized dendritic array of actin filaments. Motility is driven by catalytic cycles of filament attachment to Wiskott–Aldrich syndrome protein (WASP)-activated actin-related protein (Arp)2/3...

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Bibliografiske detaljer
Main Authors: Le Clainche, Christophe, Pantaloni, Dominique, Carlier, Marie-France
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164447/
https://ncbi.nlm.nih.gov/pubmed/12743368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1130513100
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