Keratinocyte growth factor and the transcription factors C/EBPα, C/EBPδ, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells

Strategies to stimulate endogenous surfactant production require a detailed understanding of the regulation of lipogenesis in alveolar type II cells. We developed culture conditions in which keratinocyte growth factor (KGF) stimulates fatty acid and phospholipid synthesis. KGF stimulated acetate inc...

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Main Authors: Mason, Robert J., Pan, Tianli, Edeen, Karen E., Nielsen, Larry D., Zhang, Feijie, Longphre, Malinda, Eckart, Michael R., Neben, Steven
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC164284/
https://ncbi.nlm.nih.gov/pubmed/12865412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316793
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