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Increased plasma phenylacetic acid in patients with end-stage renal failure inhibits iNOS expression

NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines. Reduced NO production due to inhibition of either eNOS or iNOS may therefore reinforce atherosclerosis. Pati...

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Detalhes bibliográficos
Main Authors: Jankowski, J., van der Giet, M., Jankowski, V., Schmidt, S., Hemeier, M., Mahn, B., Giebing, G., Tölle, M., Luftmann, H., Schlüter, H., Zidek, W., Tepel, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164281/
https://ncbi.nlm.nih.gov/pubmed/12865413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315524
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