Hemagglutinin (HA) Proteins from H1 and H3 Serotypes of Influenza A Viruses Require Different Antigen Designs for the Induction of Optimal Protective Antibody Responses as Studied by Codon-Optimized HA DNA Vaccines

Effective antibody responses provide crucial immunity against influenza virus infection. The hemagglutinin (HA) protein is the major target of protective antibody responses induced by viral infection and by vaccination with both inactivated and live-attenuated flu vaccines, but knowledge about the o...

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Main Authors: Wang, Shixia, Taaffe, Jessica, Parker, Christopher, Solórzano, Alicia, Cao, Hong, García-Sastre, Adolfo, Lu, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642598/
https://ncbi.nlm.nih.gov/pubmed/16987975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01065-06
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