Novel Fiber-Dependent Entry Mechanism for Adenovirus Serotype 5 in Lacrimal Acini

The established mechanism for infection of most cells with adenovirus serotype 5 (Ad5) involves fiber capsid protein binding to coxsackievirus-adenovirus receptor (CAR) at the cell surface, followed by penton base capsid protein binding to α(v) integrins, which triggers clathrin-mediated endocytosis...

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Autores principales: Xie, Jiansong, Chiang, Lilian, Contreras, Janette, Wu, Kaijin, Garner, Judy A., Medina-Kauwe, Lali, Hamm-Alvarez, Sarah F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642591/
https://ncbi.nlm.nih.gov/pubmed/16987972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00857-06
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