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Hepatitis C Virus Entry Requires a Critical Postinternalization Step and Delivery to Early Endosomes via Clathrin-Coated Vesicles

Hepatitis C virus (HCV) is a major human pathogen associated with life-threatening liver disease. Entry into hepatocytes requires CD81 and a putative second receptor. In this study, we elucidated the postreceptor attachment stages of HCV entry using HCV pseudoparticles (HCVpp) as a model system. By...

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Bibliographic Details
Main Authors: Meertens, Laurent, Bertaux, Claire, Dragic, Tatjana
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1642584/
https://ncbi.nlm.nih.gov/pubmed/17005647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01717-06
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