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High-Level Expression of Truncated Surface Antigen P50 of Babesia gibsoni in Insect Cells by Baculovirus and Evaluation of Its Immunogenicity and Antigenicity

Previously, we identified an immunodominant antigen, P50 of Babesia gibsoni. In the present study, the gene encoding the truncated P50 (rP50t) without a C-terminal hydrophobic region (29 amino acids [aa]) was expressed in insect cells by a recombinant baculovirus. The highly hydrophobic C-terminal 2...

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Udgivet i:Clin Diagn Lab Immunol
Principais autores: Fukumoto, Shinya, Xuan, Xuenan, Kadota, Kimie, Igarashi, Ikuo, Sugimoto, Chihiro, Fujisaki, Kozo, Nagasawa, Hideyuki, Mikami, Takeshi, Suzuki, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Microbial Immunology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12853391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.10.4.596-601.2003
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