Cloning and characterization of an aminoglycoside 6'-N-acetyltransferase gene from Citrobacter freundii which confers an altered resistance profile.

A novel gene encoding a 6'-N-aminoglycoside acetyltransferase, aac(6')-In, has been cloned and sequenced from Citrobacter freundii 13996-19, a clinical isolate from Venezuela. This gene mediates resistance to amikacin, 2'-N-ethylnetilmicin, isepamicin, kanamycin, netilmicin, and tobramycin. The aac(...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Wu, H Y, Miller, G H, Blanco, M G, Hare, R S, Shaw, K J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164142/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2439
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