Heat-induced superaggregation of amphotericin B reduces its in vitro toxicity: a new way to improve its therapeutic index.
Superaggregation of amphotericin B (AmB) was previously shown to occur upon heating of solutions at 70 degrees C. In the present study, we demonstrate that heat pretreatment of Fungizone (deoxycholate salt of AmB [AmB-DOC]) solutions induces a drastic decrease in the in vitro toxicity of this antibi...
-д хадгалсан:
| -д хэвлэсэн: | Antimicrob Agents Chemother |
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| Үндсэн зохиолчид: | , , , |
| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
American Society for Microbiology (ASM)
1997
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164126/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.11.2345 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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