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Activities of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor nelfinavir mesylate in combination with reverse transcriptase and protease inhibitors against acute HIV-1 infection in vitro.

Nelfinavir mesylate (formerly AG1343) is a potent and selective, nonpeptidic inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that was discovered by protein structure-based design methodologies. We evaluated the antiviral and cytotoxic effects of two-drug combinations of nelfinavir...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Patick, A K, Boritzki, T J, Bloom, L A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2159
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