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Mechanism of sulfonamide resistance in clinical isolates of Streptococcus pneumoniae.

The genetic basis of sulfonamide resistance in six clinical isolates of Streptococcus pneumoniae was demonstrated to be 3- or 6-bp duplications within sulA, the chromosomal gene encoding dihydropteroate synthase. The duplications all result in repetition of one or two amino acids in the region from...

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Bibliografiske detaljer
Main Authors: Maskell, J P, Sefton, A M, Hall, L M
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164080/
https://ncbi.nlm.nih.gov/pubmed/9333035
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