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Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin.

We analyzed the uptake of RU 64004 by human neutrophils (polymorphonuclear leukocytes [PMNs]) relative to those of azithromycin and roxithromycin. RU 64004 was strongly and rapidly accumulated by PMNs, with a cellular concentration/extracellular concentration ratio (C/E) of greater than 200 in the f...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Vazifeh, D, Abdelghaffar, H, Labro, M T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2099
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