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Analysis of ahpC gene mutations in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis.

The ahpC genes of 57 clinical isolates and one in vitro mutant of Mycobacterium tuberculosis were evaluated by nucleotide sequence analyses. Although compensatory ahpC promoter mutations were identified in 8 catalase-negative, katG-defective strains, the ahpC genes of 25 catalase-positive, isoniazid...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kelley, C L, Rouse, D A, Morris, S L
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303417/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.2057
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