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Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages.

The combination of clarithromycin and pyrazinamide was found to be synergistic against Mycobacterium tuberculosis in human macrophages. MICs were four- to eightfold lower for this combination than they were for either drug alone. Clarithromycin and rifampin, however, had only an additive effect.

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Bibliographic Details
Main Authors: Mor, N, Esfandiari, A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC164062/
https://ncbi.nlm.nih.gov/pubmed/9303411
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