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Efficacy of nikkomycin Z against experimental pulmonary blastomycosis.

Nikkomycin Z is a chitin synthetase inhibitor. In vitro, nikkomycin Z had good activity against Blastomyces dermatitidis, with an MIC of 0.78 microg/ml and a minimal fungicidal concentration of 3.1 microg/ml. The efficacies of various treatment durations (3, 5, or 10 days) and doses (200, 400, or 1,...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Clemons, K V, Stevens, D A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.2026
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