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Penicillin-binding proteins and induction of AmpC beta-lactamase.

In competition assays for radiolabeled penicillin, penicillin-binding proteins (PBPs) 4, 7a, and 7b showed very high affinities for strong inducers of AmpC beta-lactamase. Loss of PBP 4 resulted in diminished inducibility. This suggests that if PBPs are involved in induction of AmpC beta-lactamase,...

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Salvato in:
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Sanders, C C, Bradford, P A, Ehrhardt, A F, Bush, K, Young, K D, Henderson, T A, Sanders, W E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1997
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9303404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.9.2013
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